Mechanisms of Disease: oxidative stress and inflammation in the pathogenesis of hypertension
SUMMARY
Animal studies have shown that oxidative stress and renal tubulointerstitial inflammation are associated with, and have major roles in, the pathogenesis of hypertension. This view is supported by the observations that alleviation of oxidative stress and renal tubulointerstitial inflammation reduce arterial pressure in animal models. Conversely,
hypertension has been shown to cause ...
Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength
ABSTRACT
PURPOSE: The objective of this study was to investigate whether high levels of serum interleukin (IL)-6, C-reactive protein (CRP), and 1-antichymotrypsin (ACT) were associated with the loss of muscle strength or muscle mass (sarcopenia) in older persons.
SUBJECTS: The study included 986 men and women of the Longitudinal Aging Study Amsterdam, with a mean age of 74.6 years (standard deviation 6.2).
METHODS: ...
The anti-inflammatory effect of exercise
Petersen, Anne Marie W., and Bente Klarlund Pedersen. The anti-inflammatory effect of exercise. J Appl Physiol 98: 1154 –1162, 2005; doi:10.1152/japplphysiol. 00164.2004.—Regular exercise offers protection against all-cause mortality, primarily by protection against cardiovascular disease and Type 2 diabetes mellitus. The latter disorders have been associated with chronic low-grade systemic inflammation reflected by a two- to threefold elevated ...
C-Reactive Protein Levels and Outcomes after Statin Therapy
Abstract
Background
Statins lower the levels of low-density lipoprotein (LDL) cholesterol and C-reactive protein (CRP). Whether this latter property affects clinical outcomes is unknown.
Methods
We evaluated relationships between the LDL cholesterol and CRP levels achieved after treatment with 80 mg of atorvastatin or 40 mg of pravastatin per day and the risk of recurrent myocardial infarction or death from coronary causes ...
Ana Vládia
Nutricionista
Profª Técnica Dietética na UF Juiz de Fora
Trabalha com Pesquisa, Ensino e Extensão com foco na análise de alimentos e desenvolvimento de produtos.
Lactobacillus and Bifidobacterium improved physiological function and cognitive ability in aged mice by the regulation of gut microbiota
Scope: Age-related degeneration is associated with imbalances of gut microbiota and its related immune system, thereby gut microbiota dysbiosis is considered to be a key target to improve senescence. The potential roles of probiotics on physiological function and cognitiveability in aged mice were investigated in this study.Methods and results: Lactobaci...
Evaluation of the in vitro release of isoflavones from soybean germassociated with kefir culture in the gastrointestinal tract and anxiolytic and antidepressant actions in zebrafish (Danio rerio)
A B S T R A C TThe gastrointestinal tract contains thousands of microorganisms present in the mucosa, derived from several different species, and these microorganisms have a direct relationship with immunity, homeostasis, and certain systemic diseases. The microorganisms present in kefir grains ...
Evaluation of a potentially probiotic non-dairy beverage developed with honey and kefir grains: Fermentation kinetics and storage study
AbstractThe aim of this work was to study the fermentation process of honey with kefir grains through a comprehensive understanding of its rheological properties, probiotic cell viability, instrumental color parameters andkinetic aspects in a batch bioreactor and during storage. The results showed that kefir grains were well adapted to bioreactor conditio...
