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  • Dieta Paleo – Artigo 16

     Paleolithic and Mediterranean Diet Pattern Scores and Risk of Incident, Sporadic Colorectal Adenomas The Western dietary pattern is associated with higher risk of colorectal neoplasms. Evolutionary discordance could explain this association.We investigated associations of scores for 2 proposed diet patterns, the “Paleolithic” and the Mediterranean, with incident, sporadic colorectal adenomas in a case-control study of colorectal polyps...
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  • Dieta Paleo – Artigo 15

     Neandertal versus Modern Human Dietary Responses to Climatic Fluctuations The Neandertal lineage developed successfully throughout western Eurasia and effectively survived the harsh and severely changing environments of the alternating glacial/interglacial cycles from the middle of the Pleistocene until Marine Isotope Stage 3. Yet, towards the end of this stage, at the time of deteriorating climatic conditions that eventually led to ...
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  • Dieta Paleo – Artigo 14

     Natural environments, ancestral diets, and microbial ecology: is there a modern “paleo-deficit disorder”? Part I Famed microbiologist René J. Dubos (1901–1982) was an early pioneer in the developmental origins of health and disease (DOHaD) construct. In the 1960s, he conducted groundbreaking experimental research concerning the ways in which early-life experience with nutrition, microbiota, stress, and other environmental variables ...
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  • Dieta Paleo – Artigo 13

     Impacts of Plant-Based Foods in Ancestral Hominin Diets on the Metabolism and Function of Gut Microbiota In Vitro Ancestral human populations had diets containing more indigestible plant material than present-day diets in industrialized countries. One hypothesis for the rise in prevalence of obesity is that physiological mechanisms for controlling appetite evolved to match a diet with plant fiber content higher than that of present-day ...
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  • Dieta Paleo – Artigo 13

     Hype or Reality: Should Patients with Metabolic Syndromerelated NAFLD be on the Hunter-Gatherer (Paleo) Diet to Decrease Morbidity? The current Western diet figures centrally in the pathogenesis of several chronic diseases such as obesity, type 2 diabetes, cardiovascular disease and the emerging major health problem nonalcoholic fatty liver disease, all of them negatively impacting on life expectancy. This type of diet is represented by a ...
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  • Dieta Paleo – Artigo 12

     From lifetime to evolution: timescales of human gut microbiota adaptation Human beings harbor gut microbial communities that are essential to preserve human health. Molded by the human genome, the gut microbiota (GM) is an adaptive component of the human superorganisms that allows host adaptation at different timescales, optimizing host physiology from daily life to lifespan scales and human evolutionary history. The GM continuously ...
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  • Dieta Paleo – Artigo 11

     Favourable effects of consuming a Palaeolithictype diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study Abstract Background: The main goal of this randomized controlled single-blinded pilot study was to study whether, independent of weight loss, a Palaeolithic-type diet alters characteristics of the metabolic syndrome. Next we searched for outcome variables that might become favourably influenced by a ...
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  • Dieta Paleo – Artigo 10

     Established dietary estimates of net acid production do not predict measured net acid excretion in patients with Type 2 diabetes on Paleolithic-Hunter-Gatherer-type diets Background—Formulas developed to estimate diet-dependent net acid excretion (NAE) generally agree with measured values for typical Western diets. Whether they can also appropriately predict NAE for "Paleolithic-type" (Paleo) diets – which contain very high amounts of ...
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