Nutrição e Obesidade – Artigo 2
										
										Bariatric Surgery and Precision Nutrition
Abstract: This review provides a literature overview of new findings relating nutritional genomics and bariatric surgery. It also describes the importance of nutritional genomics concepts in personalized bariatric management. It includes a discussion of the potential role bariatric surgery plays in altering the three pillars of nutritional genomics: nutrigenetics, nutrigenomics, and epigenetics. We present studies that show the effect of each patient’s genetic and epigenetic variables on the response to surgical weight loss treatment. We ...								           
                                    
										
										
									  
								 
								
														
							
														
							
														
						
														
						
							
                                                
					                    
                                      
                         
							
							
							
								
                                
                            
									
                                  
										
																		   
									     
									                                    
										
                                                                       
									
									
									
									
										
										Nutrição e Obesidade – Artigo 1
										
										An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity
Abstract: In the past three decades, total fat and saturated fat intake as a percentage of total calories has continuously decreased in Western diets, while the intake of omega-6 fatty acid increased and the omega-3 fatty acid decreased, resulting in a large increase in the omega-6/omega-3 ratio from 1:1 during evolution to 20:1 today or even higher. This change in the composition of fatty acids parallels a significant increase in the prevalence of overweight and obesity. Experimental studies have ...								           
                                    
										
										
									  
								 
								
														
							
														
							
														
						
														
						
							
                                                
					                    
                                      
                         
							
							
							
								
                                
                            
									
                                  
										
																		   
									     
									                                    
										
                                                                       
									
									
									
									
										
										Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 20
										
										Vitamin D in amyotrophic lateral sclerosis
Summary
Vitamin D supplementation has been proposed as a potential treatment to delay amyotrophic lateral sclerosis (ALS) progression. The aims of this study were to compare retrospectively vitamin D blood levels in ALS patients with those in healthy subjects; to correlate vitamin
D blood levels with clinical functions in patients; and to evaluate whether administration of vitamin D could modify the clinical progression of the disease. Vitamin D blood levels were evaluated in 57ALS patients and in 57 healthy subjects. In the ALS patients ...								           
                                    
										
										
									  
								 
								
														
							
														
							
														
						
														
						
							
                                                
					                    
                                      
                         
							
							
							
								
                                
                            
									
                                  
										
																		   
									     
									                                    
										
                                                                       
									
									
									
									
										
										Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 19
										
										The influence of the initial state of nutrition on the lifespan of patients with
amyotrophic lateral sclerosis (ALS) during home enteral nutrition
La influencia del estado inicial de la nutrición en la esperanza de vida de pacientes con esclerosis lateral amiotrófica (ALS) durante la nutrición enteral en casa
Resumen
Objetivo: la esclerosis lateral amiotrófica (ELA) es una enfermedad crónica, neurodegenerativa que genera malnutrición. El objetivo principal de este estudio es analizar el impacto de la malnutrición en el curso de la enfermedad y la sobrevida a largo plazo.
Mat...								           
                                    
										
										
									  
								 
								
														
							
														
							
														
						
														
						
							
                                                
					                    
                                      
                         
							
							
							
								
                                
                            
									
                                  
										
																		   
									     
									                                    
										
                                                                       
									
									
									
									
										
										Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 18
										
										Pesticide exposure assessed through agricultural crop proximity and risk of
amyotrophic lateral sclerosis 
Abstract
Background: Epidemiologic studies have raised the possibility that some pesticide compounds induce the neurodegenerative disease amyotrophic lateral sclerosis (ALS), though the available evidence is not entirely consistent.
Methods: We conducted a population-based case-control study in two Italian populations to assess the extent to which residence in the vicinity of agricultural crops associated with the application of neurotoxic pesticides is a risk factor for ALS, ...								           
                                    
										
										
									  
								 
								
														
							
														
							
														
						
														
						
							
                                                
					                    
                                      
                         
							
							
							
								
                                
                            
									
                                  
										
																		   
									     
									                                    
										
                                                                       
									
									
									
									
										
										Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 17
										
										Manejo nutricional de la esclerosis lateral amiotrófica: resumen de recomendaciones
Nutritional management of amyotrophic lateral sclerosis: summary of recommendations
CONCLUSIONES
La ELA es la más común de las enfermedades de la motoneurona. Con una incidencia en España cercana a un nuevo caso por 100.000 habitantes/año, no es muy habitual encontrarnos este
tipo de pacientes en las consultas de Nutrición, por lo que contar con una guía de manejo resulta especialmente útil. La ELA afecta gravemente al proceso de alimentación y al estado nutricional. Está demostrado que la ...								           
                                    
										
										
									  
								 
								
														
							
														
							
														
						
														
						
							
                                                
					                    
                                      
                         
							
							
							
								
                                
                            
									
                                  
										
																		   
									     
									                                    
										
                                                                       
									
									
									
									
										
										Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 16
										
										Lead, cadmium and mercury in cerebrospinal fluid and risk of amyotrophic lateral sclerosis: a case-control study
Abstract
Exposure to neurotoxic chemicals such as pesticides, selenium, and heavy metals have been
suggested to play a role in the etiology of amyotrophic lateral sclerosis (ALS). We assessed
exposure to lead, cadmium, and mercury in 38 ALS patients (16 men and 22 females) and 38
hospital-admitted controls by using their cerebrospinal fluid (CSF) content as biomarker. We
determined CSF heavy metal levels with inductively coupled plasma sector field mass
spectrometry, ...								           
                                    
										
										
									  
								 
								
														
							
														
							
														
						
														
						
							
                                                
					                    
                                      
                         
							
							
							
								
                                
                            
									
                                  
										
																		   
									     
									                                    
										
                                                                       
									
									
									
									
										
										Nutrição e ELA (Esclerose Lateral Amiotrófica) – Artigo 15
										
										Intakes of caffeine, coffee and tea and risk of Amyotrophic Lateral Sclerosis: Results from five cohort studies 
Abstract
Objective—Caffeine is thought to be neuroprotective by antagonizing the adenosine A2A
receptors in the brain and thereby protecting motor neurons from excitotoxicity. We examined the association between consumption of caffeine, coffee and tea and risk of Amyotrophic Lateral
Sclerosis (ALS).
Methods—Longitudinal analyses based on over 1 010 000 men and women in 5 large cohort
studies [the Nurses’ Health Study, the Health Professionals Follow-up Study, the ...